Oueslati LAB
Cellular and Molecular
Neurodegeneration
Publications
2017
Dahmene M, Bérard M, Oueslati A. Dissecting the molecular pathway involved in PLK2-mediated α-synuclein selective autophagic degradation. J Biol Chem. 2017 Jan 30 (IF: 4.6).
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2016 (3 articles)
Jeon I, Cicchetti F, Cisbani G, Lee S, Li E, Bae J, Lee N, Li L, Im W, Kim M, Kim HS, Oh SH, Kim TA, Ko JJ, Aubé B, Oueslati A, Kim YJ, Song J. Human-to-mouse prion-like propagation of mutant huntingtin protein. Acta Neuropathol. 2016 (IF: 10.8)
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Oueslati A. Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?
J Parkinsons Dis. 2016;6(1):39-51.(IF: 1.9)
Mohamed-Bilal Fares, Bohumil Maco, Abid Oueslati, Edward Rockenstein, Natalia Ninkina, Vladimir L Buchman, Eliezer Masliah, Hilal A Lashuel. Induction of de novo α-Synuclein fibrillization in a novel neuronal model for Parkinson's disease. Proc Natl Acad Sci U S A, 2016; 113(7):E912-21. (IF: 9.8).
2015 (2 articles)
Abid Oueslati, Blaise Lovisa, John Perrin, George Wagnières , Hubert van den Bergh , Yanik Tardy, Hilal A. Lashuel. Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson's Disease. PLoS One. 2015;10(10). (IF: 3.5).
Martial Mbefo, Mohamed-Bilal Fares, Katerina Paleologou, Abid Oueslati, Guowei Yin, Sanda Tenreiro, Madalena Pinto, Tiago Outeiro, Markus Zweckstetter, Eliezer Masliah, and Hilal A. Lashuel. The Parkinson's disease mutant E46K enhances alpha-synuclein phosphorylation in mammalian cell lines, in yeast and in vivo. J. Biol. Chem 2015 (Epub ahead of print). (IF: 4.6).
2014 (3 articles)
Abid Oueslati*, Methodios Ximerakis and Kostas Vekrellis. Protein transmission, seeding and degradation: Key steps for α-synuclein prion-like propagation. Exp. Neurobiol. 2014. 23(4): 324-36 (* corresponding author). (IF: 2.5).
Ossama Khalaf*, Bruno Fauvet*, Abid Oueslati*, Igor Dikiy, Anne-Laure Mahul-Mellier, Francesco S. Ruggeri, Martial Mbefo, Filip Vercruysse, Giovanni Dietler, Seung-Jae Lee, David Eliezer, and Hilal A. Lashuel. The Parkinson’s disease-linked mutation H50Q enhances α-synuclein aggregation, secretion and toxicity. J. Biol. Chem. 2014. 289(32): 21856-76 (*co-first authors). (IF: 4.6).
Anne-Laure Mahul-Mellier, Bruno Fauvet, Amanda Gysbers, Igor Dikiy, Abid Oueslati, Sandrine Georgeon, Allan Joaquim Lamontanara, Alejandro Bisquertt, David Eliezer, Eliezer Masliah, Glenda Halliday, Oliver Hantschel and Hilal A. Lashuel. c-Abl phosphorylates α-syn and regulates its degradation, implication for α-syn clearance and contribution to the pathogenesis of Parkinson's Disease. Hum Mol Genet. 2014 23(11): 2858-79. (IF: 6.9).
2013 (1 article)
Abid Oueslati, Bernard L. Schneider, Patrick Aebischer, Hilal A. Lashuel. PLK2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo. Proc Natl Acad Sci U S A, 2013; 110 (41): E3945-54. (IF: 9.8).
2012 (2 articles)
Hilal A. Lashuel, Cassia R. Overk, Abid Oueslati and Eliezer Masliah. The many faces of α-synuclein: from structure and toxicity to therapeutic strategies. Nature Reviews Neuroscience. 2012; 14(1): 38-48. (IF: 31.37).
Abid Oueslati, Katerina E. Paleologou, Bernard L. Schneider, Patrick Aebischer, Hilal A. Lashuel. Mimicking phosphorylation at Serine 87 inhibits the aggregation of human alpha-synuclein and protects against its toxicity in a rat model of Parkinson’s disease. J. Neurosci. 2012; 32(5): 1536-1544. (IF: 6.9).
2010 (3 articles)
Katerina E. Paleologou*, Abid Oueslati*, Gideon Shakked, Carla C. Rospigliosi , Hai-Young Kim, Gonzalo R. Lamberto, Claudio O. Fernandez, Adrian Schmid, Wei Ping Gai, Diego Chiappe, Marc Moniatte, Bernard Schneider, Patrick Aebischer, David Eliezer, Markus Zweckstetter, Eliezer Masliah, Hilal A. Lashuel. Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences alpha-synuclein-membrane interactions. J. Neurosci. 2010; 30 (9): 3184-3198. (* co-first authors). (IF: 6.9).
Abid Oueslati*, Margot Fournier*, Hilal A Lashuel. The Role of the Post-Translational Modifications in Modulating the Structure, the Function and the Toxicity of Alphα-synuclein: Implication for Parkinson’s Disease Pathogenesis. Prog Brain Res. 2010; 183:115-45 (*co-first authors). (IF: 5.1).
Martial K. Mbefo, Katerina E. Paleologou, Ahmed Boucharaba, Abid Oueslati, Diana Olschewski, Heinrich Schell, Eliezer Masliah, Philipp Khale, Harald Hirling, and Hilal A. Lashuel. Phosphorylation Of Synucleins By Members Of The Polo-Like Kinase Family. J Biol Chem, 2010; 285 (4): 2807-2822. (IF: 4.6).
2009 (1 article)
Emilie Lacombe, Vitaly Khaindrava, Christophe Melon, Abid Oueslati, Lydia Kerkerian-Le Goff and Pascal Salin. Different functional basal ganglia subcircuits associated with anti-akinetic and dyskinesiogenic effects of antiparkinsonian therapies. Neurobiol Dis. 2009; 36 (1): 116-125. (IF: 5.2).
2007 (1 article)
Abid Oueslati, Véronique Sgambato-Faure, Christophe Melon, Philippe Kachidian, Paolo Gubellini, Mohammed Amri, Lydia Kerkerian-Le Goff, Pascal Salin. High frequency stimulation of the subthalamic nucleus potentiates L-DOPA-induced neurochemical changes in the striatum in a rat model of Parkinson’s disease. J. Neurosci., 2007; 27 (9): 2377–2386. (IF: 6.9).
2006 (1 article)
Paolo Gubellini, Alexandre Eusebio, Abid Oueslati, Christophe Melon, Lydia Kerkerian-Le Goff, Pascal Salin. Chronic stimulation of the subthalamic nucleus and dyskinetogenic L-DOPA treatment: differential effects in a rat model of Parkinson's disease. Eur. J. Neurosci. 2006; 24 (6): 1802–1814. (IF: 3.66).
2005 (1 article)
Abid Oueslati, Nathalie Breysse, Marianne Amalric, Lydia Kerkerian-Le Goff, Pascal Salin. Dysfunction of the cortico-basal ganglia-cortical loop in a rat model of early parkinsonism is reversed by metabotropic glutamate receptor 5 antagonism. Eur. J. Neurosci. 2005; 22(11): 2765-2774. (IF: 3.66).